Full Thickness Skin Expansion ex vivo in a Newly Developed Reactor and Evaluation of Auto-Grafting Efficiency of the Expanded Skin Using Yucatan Pig Model

Skin bioreactor and grafting procedure. A Skin was expanded on the bioreactor. B–D Full-thickness porcine inguinal skin with an area of 4 cm × 4 cm (B) was removed and measured (C), and then expanded and incubated in the bioreactor for 48 h (D). E Recipient dorsal skin with an area of 6 cm × 6 cm was removed. F The expanded skin was grafted on the dorsal ski