Usefulness of the APTT waveform for the diagnosis of DIC and prediction of the outcome or bleeding risk

The APTT waveform in a healthy volunteer (a), a patient without DIC (b), a patient with pre-DIC (c), a patients with DIC without hypofibrinogenemia (d) and a patient with DIC with hypofibrinogenemia (e). a, 2nd derivative; b, negative acceleration, c, 1st derivative; d, coagulation curve, 1, time for peak; 2, height of peak; 3, width of pea