AB014. Sunitinib affects autophagy and apoptosis via regulation of glycolysis in renal cell carcinoma cells

Renal cell carcinoma (RCC) is resistant to regular chemotherapy and radiation. Sunitinib, which targeted to VEGF receptor and other signal pathways, has been proved effective for prolonged cancer specific survival and overall survival for metastatic RCC. There is no report on autophagy induced by sunitinib in RCC cells yet