Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells

DOI: 10.1016/j.toxrep.2018.02.008

Keywords: ACC, acetyl-CoA carboxylase, AMPK, AMP-activated protein kinase, aP2, fatty acid binding protein (aP2), BCS, bovine calf serum, C/EBPα, CCAAT/enhancer-binding protein α, CQR-300, Cissus quadrangularis extract, DMEM, Dulbecco’s modified Eagle’s medium, FAS, fatty acid synthase, FAS-α, fatty-acid synthase, FBS, fetal bovine serum, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, LPL, lipoprotein lipase, MDI, medium dependent interface, MTT, 3-(4, 5-dimetylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide, ORO, Oil-red O, p-AMPK, phosphorylated-AMPK, PPARγ, peroxisome proliferator-activated receptor γ, RIPD, radioimmunoprecipitation assay buffer, SCD-1, stearoyl-CoA desaturase-1, SREBP-1c, sterol regulatory element binding protein-1c, TG, triglycerides Adipocytes, Adipogenesis, Anti-obesity, Cissus quadrangularis extract (CQR-300), Lipogenesis

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