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OALib Journal期刊
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-  2018 

7SK small nuclear RNA, a multifunctional transcriptional regulatory RNA with gene-specific features

DOI: 10.1080/21541264.2017.1344346

Keywords: 7SK snRNA, 7SK snRNP, P-TEFb, RNA polymerase II pausing, transcription regulation

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Abstract:

The 7SK small nuclear RNA is a multifunctional transcriptional regulatory RNA that controls the nuclear activity of the positive transcription elongation factor b (P-TEFb), specifically targets P-TEFb to the promoter regions of selected protein-coding genes and promotes transcription of RNA polymerase II-specific spliceosomal small nuclear RNA genes

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