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-  2018 

Signal transducer and activator of transcription?3 overexpression promotes lymph node micrometastasis in early‐stage non‐small cell lung cancer

DOI: 10.1111/1759-7714.12598

Keywords: Lymph node micrometastasis, mucin?1, non‐small cell lung cancer, phosphorylated signal transducer and activator of transcription?3, signal transducer and activator of transcription?3

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Abstract:

Signal transducer and activator of transcription?3 (STAT3) is constitutively activated in several malignancies. Here, we define the correlation between STAT3 expression and lymph node micrometastasis of early‐stage non‐small cell lung cancer. Then we highlight some possibilities associated with developing a way to detect tumor micrometastasis and an anticancer drug that might therapeutically inhibit the STAT3 signaling pathway

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