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ISSN: 2333-9721
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-  2019 

Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia

DOI: 10.1038/s41398-019-0398-5

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Abstract:

Schizophrenia-associated index SNPs were obtained from public GWASs databases. LD analyses were carried out using the 1000 genome data and GWASs summary data were used to obtain all schizophrenia susceptibility SNPs. Functional annotation was carried out according to the genomic regions of all susceptibility SNPs. For annotated functional SNPs, histone modification enrichment, meQTL, eQTL, and pQTL analyses then were carried out. Various methods were used to validate target gene

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