Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach

The analysis process designed for identifying molecular variants that may contribute to SZ-spectrum disorders in a multiplex 22q11.2DS family. Filled symbols indicate 22q11.2DS affected person with the same 22q11.2 deletion (CGH-array: chr22:18,844,632-21,703,145, GRCh37). *No DNA was available for these family members. BPE brief psychotic episode, CGH comparative-genomic hybridization, CNV copy number variation, DD delusional disorder, MLPA multiplex ligation probe amplification, SZ schizophreni