Assessment of 4 Cases of Kidney Transplantation from Hepatitis C Virus Antibody-Positive and RNA-Negative Donors to Antibody-Negative Recipients

Hepatitis C virus (HCV) infection is significantly more prevalent among hemodialysis patients than the general population,1 and caution is required when evaluating these patients for kidney transplantation. It has been reported that HCV infection may develop in uninfected recipients receiving organs from HCV-infected donors2 and that transplantation increases the risk of liver disease2 and mortality.3 Therefore, at many institutions, kidneys from HCV antibody-positive donors are not allowed to be used for transplantation, regardless of the HCV RNA level