Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles

Procedures of preparation for M5BT/T-CAP microspheres by double emulsion (modified from the figure from sander, soft matter, 2014). A Addition of M5BT solution (water phase, W1) into T-CAP solution in DCM (organic phase, O). B 1st emulsification (W1/O emulsion). C Addition of W1/O solution into PVA solution (water phase, W2). D 2nd emulsification (W1/O/W2 emulsion). E Hardened microsphere by evaporating DCM and centifugatio