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-  2018 

Vedolizumab and early postoperative complications in nonintestinal surgery: a case-matched analysis

DOI: 10.1177/1756284818783614

Keywords: antibodies, infection, inflammatory bowel diseases, integrins, monoclonal, postoperative complications

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Abstract:

Vedolizumab (VDZ) is a gut-specific α4-β7 integrin antagonist that has demonstrated efficacy in Crohn’s disease (CD) and ulcerative colitis (UC). The safety of VDZ in the perioperative period remains unclear. The aim of this study was to evaluate postoperative complications and perioperative safety in VDZ-treated patients undergoing nonintestinal operations

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