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OALib Journal期刊
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-  2018 

Direct oral anticoagulants for stroke prevention in atrial fibrillation: treatment outcomes and dosing in special populations

DOI: 10.1177/1753944718787384

Keywords: direct oral anticoagulants, dosing recommendations, nonvalvular atrial fibrillation, special populations, stroke prevention

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Abstract:

To review data from the pivotal phase III trials evaluating the efficacy and safety of direct oral anticoagulants (DOACs) versus warfarin for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF), and to summarize the major findings with regards to patient subgroups that are at an increased risk for stroke or bleeding

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