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-  2017 

Increased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6

DOI: 10.2147/PGPM.S114211

Keywords: cohort study, pharmacogenomics, emergency department, hospitalization

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Abstract:

Cytochrome P450 2D6 (CYP2D6) is responsible for the metabolism of clinically used drugs and other environmental exposures, but it is unclear whether the CYP2D6 phenotype is associated with adverse health outcomes. The aim was to determine the association of CYP2D6 phenotype with the risk of hospitalization or an emergency department (ED) visit among a group of primary care patients

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