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-  2019 

Natural killer cells limit the clearance of senescent lung adenocarcinoma cells

DOI: 10.1038/s41389-019-0133-3

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Abstract:

a Representative bioluminescent optical imaging of Foxn1nu/nu mice transplanted with KPrLG cells. The initial treatment with corn oil (Control) or tamoxifen (Restored) is defined as day 0. Subsequent treatments indicated by arrows on x-axis. Images, relative to day 0 are from the same animal at the indicated time points. b Quantification of bioluminescent images from NCR:Foxn1nu/nu mice. Corn oil or tamoxifen was administered on day 0 and day 3. Data shown are combined from two independent KPr cell lines. c Quantification of bioluminescent images from C57BL6/J:Rag1-/- mice. Corn oil or tamoxifen was administered on days 0, 1, and 2 (arrows). Analysis of significance between control and restored groups was performed by t-test at day 10 test (Foxn1nu/nu) day 6 (C57BL6/J:Rag1-/-

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