Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56

A–C TRIM56 mRNA level correlates with poor endocrine treatment outcome in breast cancer patients. Each panel is derived from independent clinical cohorts. These clinical data are acquired from KMPLOT database (http://kmplot.com/analysis/). D Examples of positive/negative TRIM56, ERα, PR and HER2 staining in breast tumor samples were shown by ×100 magnification. The statistical data of each protein marker are shown in Table Table1