Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rgnull mice

V.S.D. and A.D.D. designed the experiments, supervised the performance of the experiments, analyzed the data, wrote the majority of the manuscript, and are guarantors of the reported results. A.H. designed, performed, and analyzed the immunohistochemistry experiments and contributed Materials and Methods section to the manuscript. P.B. supervised the circulating tumor cell tumorigenicity experiments. J.P.R. supervised the tumorigenicity experiment with MCF7 cells