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-  2016 

Brain development in adolescents at ultra-high risk for psychosis: Longitudinal changes related to resilience

DOI: 10.1016/j.nicl.2016.08.013

Keywords: Ultra-high risk, Psychosis, Resilience, MRI, Functional outcome, Brain development

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Abstract:

The main focus of studies of individuals at ultra-high risk for psychosis (UHR) has been on identifying brain changes in those individuals who will develop psychosis. However, longitudinal studies have shown that up to half of UHR individuals are resilient, with symptomatic remission and good functioning at follow-up. Yet little is known about brain development in resilient individuals. Therefore, the aim of this study was to investigate differences in brain development between resilient and non-resilient individuals

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