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- 2018
White matter microstructure is associated with language in children born very pretermDOI: 10.1016/j.nicl.2018.09.020 Keywords: Preterm birth, Language, Magnetic resonance imaging, Diffusion-weighted imaging, NODDI VPT, Very preterm, FA, Fractional anisotropy, AD, axial diffusivity, RD, radial diffusivity, MD, mean diffusivity, TBSS, Tract-Based Spatial Statistics, DTI, Diffusion Tensor Imaging, NODDI, Neurite Orientation Dispersion and Density Imaging, GA, gestational age Abstract: Very preterm birth is associated with altered white matter microstructure and language difficulties, which may compromise communication, social function and academic achievement, but the relationship between these two factors is unclear. The aim of this study was to explore associations between white matter microstructure and language domains of semantics, grammar and phonological awareness at 7-years of age on a whole-brain level and within the arcuate fasciculus, an important language pathway, in very preterm and term-born children
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