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- 2018
Neurotransmitter alterations in the anterior cingulate cortex in Crohn's disease patients with abdominal pain: A preliminary MR spectroscopy studyDOI: 10.1016/j.nicl.2018.09.008 Keywords: Brain-gut axis, Crohn's disease, Glutamate, Metabolite, Pain, Spectroscopy Abstract: Crohn's disease (CD) has been known to cause both abdominal pain alongside functional and structural alterations in the central nervous system (CNS) in affected patients. This study seeks to determine the alternations of metabolites in the bilateral anterior cingulate cortex (ACC) of CD patients with abdominal pain by using proton magnetic resonance spectroscopy (1H-MRS) to further explore the neural mechanism
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