Brain responses to vestibular pain and its anticipation in women with Genito-Pelvic Pain/Penetration Disorder
DOI: 10.1016/j.nicl.2017.07.017
Els Pazmany ,
Huynh Giao Ly ,
Jan Tack ,
Johan Verhaeghe ,
Leen Aerts ,
Lukas Van Oudenhove ,
Michiko Kano ,
Patrick Dupont ,
Paul Enzlin ,
Ronald Peeters ,
Sophie Bergeron Keywords: aMCC , anterior midcingulate cortex , dlPFC , dorsolateral prefrontal cortex , DSM-5 , Diagnostic Statistical Manual of Mental Disorders , fifth edition , FM , fibromyalgia , fMRI , functional magnetic resonance imaging , FPQ , Fear of Pain Questionnaire , GPPPD , Genito-Pelvic Pain/Penetration Disorder , HC , healthy controls , IBS , irritable bowel syndrome , n , number , OFC , orbitofrontal cortex , pACC , perigenual anterior cingulate cortex , PASS , Pain Anxiety Symptoms Scale , PVD , provoked vestibulodynia , Q1 , Quartile 1 , Q3 , Quartile 3 , SAS , statistical analysis software , SD , standard deviation , SII , secondary somatosensory cortex , SMA , supplementary motor area , SPM8 , Statistical Parametric Mapping , SPM8 , SPSS , Statistical Package for Social Sciences , STAI , State-Trait Anxiety Inventory , TR/TE , repetition time/echo time , VAS , Visual Analogue Scale , vlPFC , ventrolateral prefrontal cortex , vmPFC , ventromedial prefrontal cortex Anticipation of pain , Pain-related fear and anxiety , Vestibular pain , fMRI , Genito-pelvic pain/penetration disorder , Provoked vestibulodynia
Abstract:
In DSM-5, pain-related fear during anticipation of vaginal penetration is a diagnostic criterion of Genito-Pelvic Pain/Penetration Disorder (GPPPD). We aimed to investigate subjective and brain responses during anticipatory fear and subsequent induction of vestibular pain in women with GPPPD
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