Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress

Salidroside attenuates tunicamycin-induced ER stress. A Chemical structure of salidroside. B Western blots of ER stress sensors (BiP, p-PERK, and p-IRE1). SN4741 cells were pretreated with salidroside (Sal; 25 μmol/L) for 10 h, and then tunicamycin (Tun; 5 μmol/L) was added for an additional 24 h. (C–E) Quantification of band densities of p-IRE1, BiP, and p-PERK from B (mean ± SEM, n = 3; **P < 0.01 compared with control group, ## P < 0.01 compared with tunicamycin-treated group; one-way ANOVA)