Attenuation of β-Amyloid Toxicity In Vitro and In Vivo by Accelerated Aggregation

Schematic of the design of peptide modulators. A Specific Aβ sequences with specific targets of the peptide modulators indicated. B The peptide modulators altered Aβ42 aggregation. ThT fluorescence was monitored during incubation of 40 μmol/L Aβ42 in the absence or presence of 10 μmol/L peptide modulator. Error bars are standard deviations of the mean of three replicates