Human microbiome signatures of differential colorectal cancer drug metabolism

Two distinct metabolizer phenotypes or ‘metabotypes’ based on % SN-38 formation during a time course incubation of SN-38G with fecal samples from 20 individuals quantified by LC-MS/MS. Participants were sub-grouped into low (n？=？16) and high (n？=？4) metabolizer phenotypes. All samples were run in triplicate and values are the mean？±？se