D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization

DOI: 10.1080/2162402X.2018.1445454

Keywords: immunometabolism, oncometabolite, acute myeloid leukemia, IDH mutation, Th17, Tregs, 2HG, Immunosurveillance, Inflammation and cancer

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