Atypical GATA transcription factor TRPS1 represses gene expression by recruiting CHD4/NuRD(MTA2) and suppresses cell migration and invasion by repressing TP63 expression

a ChIP-seq density map of TRPS1-binding sites. b TRPS1- and GATA3-binding motif analysis. GATA3 motif analysis was based on data from JASPAR MA0037.339. c Genomic distribution of TRPS1 determined by ChIP-seq analysis. d Genome browser track examples of the binding of TRPS1 on representative target genes, SETD7, ABCA12, and NAALADL2. e ChIP-qPCR analysis of TRPS1 candidate target genes: ABCA12, NLGN1, NHLRC1, SETD7, RNF43, NAALADL2, and NTN4. Untr4 is a well-characterized untranscribed genomic region and used as a comparative control. Each bar represents the mean？±？SD for triplicate experiments. The t test was used for calculation of statistical significance. *p？<？0.05, **p？<？0.0