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-  2018 

LXRɑ participates in the mTOR/S6K1/SREBP-1c signaling pathway during sodium palmitate-induced lipogenesis in HepG2 cells

DOI: 10.1186/s12986-018-0268-9

Keywords: LXRα, mTOR, S6K1, NAFLD, HepG2 cells

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Abstract:

Oil Red O staining and TG content in sodium palmitate-treated HepG2 cells. a After incubation with 144 μM PA for different periods of time (a control; b PA for 24 h; and c PA for 48 h), HepG2 cells were stained with Oil Red O and reviewed under an optical microscope. b The intracellular lipid content in each group was quantified. c Cells were treated with 144 μM PA for 24 and 48 h, and TG levels were measured by an enzymatic assay kit. Data are presented as the means±SDs (*P <?0.05 versus the control group

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