Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy
DOI: 10.1080/2162402X.2017.1385690
Ana C. Anderson,
Ansgar Brock,
Catherine A. Sabatos-Peyton,
Dewar J. Tan,
Fangmin Xu,
James Nevin,
John D. Venable,
John Taraszka,
Luke Wesemann,
Max Klapholz,
Nandini Acharya,
Nasim Kassam,
Richard S. Blumberg,
Thomas Pertel,
Vijay K. Kuchroo,
Xiaomo Jiang,
Yassaman Etminan,
Yu-Hwa Huang
Keywords: antibody, checkpoint receptor, ligand, Tim-3, HDxMS
Abstract:
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