Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma

a Protein expression of Bcl-2 as detected by immunohistochemistry significantly increased with increasing histological grade, in peripheral as well as in central chondrosarcoma. b Bcl-xl is highly expressed in conventional chondrosarcoma and is increased in high grade (grade II and III) compared to ACT. c Expression of Bcl-w is low in conventional chondrosarcoma, but higher expression is observed in grade III chondrosarcoma compared to ACT. Each dot represents one tumor and mean value with standard deviation is shown for each grou