Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer

a, b BCa cells were treated with or without b-AP15. c, d BCa cells were treated with or without PtPT. Cell viability was tested using MTS assays. Mean？±？SD of three independent experiments. *p？<？0.05, #p？<？0.01, the two-sided t-test. BCa cells were treated with b-AP15 (e) and PtPT (f) for 24？h, then were transplanted in 30% agarose for 10 days. The shown images were from one of three independent experiment