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OALib Journal期刊
ISSN: 2333-9721
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-  2017 

Identification of Cysteine Ubiquitylation Sites on the Sec23A Protein of the COPII Complex Required for Vesicle Formation from the ER

DOI: 10.2174/1874091X01711010036

Keywords: Ubiquitylation, Sec23a, COPII, ERES, Vescicular transport

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Abstract:

COPII is a multiprotein complex that surrounds carrier vesicles budding from the Endoplasmic Reticulum and allows the recruitment of secretory proteins. The Sec23a protein plays a crucial role in the regulation of the dynamics of COPII formation ensuring the proper function of the secretory pathway

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