Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo

DOI: 10.2147/OTT.S161198

Keywords: gastric adenocarcinoma, V-ATPases, tumor acidity, hypoxia, proton pump inhibitors, multidrug resistance, signaling pathway

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