Oncolytic immunotherapy: The new clinical outbreak

This last year was productive for the oncolytic viruses (OV) field with numerous advancements. The 9th international conference on OV therapeutics, that has been held in Boston, USA, from the 13th to the 16th of June 2015, was the opportunity to discuss these progresses (OVC Boston 2015: the conference program with abstracts and the list of participants is available at this address: http://ovcboston.com/final-program/). It was locally organized by Nino Chiocca from Brigham and Women's Hospital and Samuel Rabkin from Massachusetts General Hospital. OV are viruses that infect preferentially or exclusively cancer cells and cause immunogenic cell death which induces or stimulates an antitumor immune response in patients.1,2 During this congress, many encouraging clinical results were presented