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OALib Journal期刊
ISSN: 2333-9721
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-  2017 

Hepatic and Aortic Arch Expression and Serum Levels of Syndecan-1 in ApoE-/- Mice

DOI: 10.2174/1874091X01711010077

Keywords: Syndecan-1, ApoE-/- mice, C57Black mice, Disordered structure, Cholesterol level, HSPG

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Abstract:

Heparan sulfate proteoglycan (HSPG) syndecan-1 (Sdc1) acts as a receptor for triglyceride-rich lipoproteins (TRLs), growth factors, chemokines and enzymes. Due to the disordered structure, its function is as diverse as its ligands. In this paper, we have analyzed hepatic and aortic arch expression of Sdc1 in ApoE-/- mice and examined their association with biochemical changes in plasma during the atheroma formation

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