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-  2019 

WHSC1 acts as a prognostic indicator and functions as an oncogene in cervical cancer

DOI: 10.2147/OTT.S204701

Keywords: Wolf–Hirschhorn syndrome candidate 1, cervical cancer, growth, angiogenesis, endothelial nitric oxide synthase

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Abstract:

Purpose: Wolf–Hirschhorn syndrome candidate 1 (WHSC1) is an epigenetic modifier, considered to play a driving role in oncogenesis. However, very little is known about the roles of WHSC1 and its prognostic impacts in cervical cancer. This study aimed to investigate the role of WHSC1 in the prognosis of cervical cancer and explore the effect of WHSC1 on proliferation, migration, and invasion of cervical cancer cells and angiogenesis in human umbilical vein endothelial cells (HUVECs)

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