Effect of Solution pH on Distribution of Ophthalmically Administered Brimonidine in Posterior Ocular Tissues in Pigmented Rabbits

Brimonidine concentration–time curves in posterior ocular tissues after a single topical administration of brimonidine tartrate ophthalmic solution in pigmented rabbits. Each pigmented rabbit was administered 35 μL of 0.2% brimonidine tartrate ophthalmic solution. Data are presented as the mean？+？standard deviation (n？=？5