A landscape view on the interplay between EMT and cancer metastasis

The diagram for the core circuit of EMT-metastasis network including 10 gene nodes and 26 regulation links (8 activations and 18 repressions). Red arrows represent activation and blue bars represent repression. Magenta nodes represents pro-metastatic genes, and cyan nodes represent anti-metastatic genes. Circle nodes represent proteins and hexagonal nodes represent microRNAs. u34: miR34, u200: miR200, u145: miR14