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-  2018 

RETROSPECTIVE STUDY OF THE RADIOLOGICAL FINDINGS OF THE MEDIASTINUM AFTER END-OF-TREATMENT FOR A MEDIASTINAL LYMPHOMATOUS MASS IN PEDIATRIC ONCOLOGY

DOI: 10.1093/pch/pxy054.111

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Abstract:

Reactive thymic hyperplasia, or rebound thymus, is a well-known phenomenon following chemotherapy. While rebound thymus has been described after treatment for many different malignancy, it has been more often noted after treatment for lymphomas. In children and adolescents in which the primary lymphoma was located in the mediastinum, a mediastinal mass, such as a reactive thymic hyperplasia, can be misdiagnosed as a tumor relapse. It can be difficult for the clinician to differentiate between a tumor relapse and a reactive thymic hyperplasia, which may cause unnecessary additional imaging and invasive diagnostic procedures as well as anxiety for the patient and his family

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