Inference and interrogation of a coregulatory network in the context of lipid accumulation in Yarrowia lipolytica

Heatmap of TF influence as a function of C/N ratio during a time-course experiment. Four main phases were identified on the basis of changes in influence pattern: phase I (t？±？？=？123.67？h, C/N ratio？=？7.89), phase II (t？=？139.58？h, C/N ratio？=？8.63), phase III (t？=？157.58？h, C/N ratio？=？20.41), and phase IV (t？=？166.08？h, C/N ratio？=？30.96). These phases are shown on the left in turquoise, yellow, purple and red, respectively. Negative and positive influences are indicated from blue to red, with color intensity proportional to the influence value. Time and C/N ratio are indicated on the right, as described by Ochoa-Estopier and Guillouet 37 and in the {"type":"entrez-geo","attrs":{"text":"GSE35447","term_id":"35447"}}GSE35447 data se