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-  2016 

No Association Between rs7077361 in ITGA8 and Parkinson’s Disease in Sweden

DOI: 10.2174/1874205X01610010025

Keywords: Association study, ITGA8, LRRK2, Parkinson’s disease, rs7077361, SNP

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Abstract:

Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson’s disease, an age related neurodegenerative disease with unknown etiology. ITGA8 is a transmembrane protein involved in several cellular processes, such as cell adhesion, migration and cytoskeletal rearrangement

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