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-  2019 

Notch pathway is involved in the suppression of colorectal cancer by embryonic stem cell microenvironment

DOI: 10.2147/OTT.S199046

Keywords: embryonic stem cell microenvironment, colorectal cancer, tumorigenicity, Notch pathway

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Abstract:

Objectives: Recently, embryonic microenvironment is being known for its non-permissive property for tumor growth. However, the regulatory mechanism to maintain the balance between differentiation and tumorigenicity of cancer cell in microenvironment is not well understood

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