Activation of Parvalbumin-Positive Neurons in Both Retina and Primary Visual Cortex Improves the Feature-Selectivity of Primary Visual Cortex Neurons

Immunohistochemistry of ChR2-tdTomato in the retina, dLGN, and V1 of ChR2fl/+; PV-Cre mice. A PV and ChR2 expression in the retina. B Expression of ChR2 in a 12-μm retinal section. C–D High magnification images of the areas labeled by the squares in A. E PV and ChR2 expression in the dLGN and V1. F High magnification of the area (V1) enclosed by the upper square in E. G High magnification of the area (dLGN) enclosed by the lower square in E. H ChR2 expression after monocular enucleation. The left dLGN was ipsilateral to the enucleated eye, whereas the right dLGN was contralateral to the enucleated eye