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-  2018 

Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia

DOI: 10.1159/000495032

Keywords: Adenocarcinoma, Oxaliplatin, Thrombocytopenia

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Abstract:

Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid tumors. Thrombocytopenia with traditional chemotherapy agents is most frequently the result of megakaryocyte cytotoxicity. Oxaliplatin is a platinum derivative commonly used in gastrointestinal malignancies and is associated with drug-induced immune thrombocytopenia

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