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-  2018 

MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A

DOI: 10.1038/s41419-017-0218-x

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Abstract:

a miR-1253 level was measured by qRT-PCR in 70 NSCLC and pair-matched lung tissue samples, and normalized against endogenous U6 RNA. b, c Expression of miR-1253 in NSCLC was associated with clinical stage (b) and lymph node metastasis (c). d Kaplan–Meier curves depicting overall survival according to the expression of miR-1253 by qRT-PCR. e The expression levels of miR-1253 in 87 paired NSCLC and corresponding noncancerous tissues were measured by in situ hybridization. f Kaplan–Meier curves depicting overall survival according to high and low miR-1253 expression in 87 patients with NSCLC by in situ hybridization; *p?

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