Selective deletion of hepatocyte platelet-derived growth factor receptor α and development of liver fibrosis in mice

Attenuation of PDGFRα expression in TAA-treated livers after conditional deletion of PDGFRα in hepatocytes. a PDGFRα in hepatocytes. b Identification of hepatocyte PDGFRα-deleted knockout (KO) mice by genotyping PCR (lane 2). c PDGFRα expression in the liver of wild-type (WT) and hepatocyte PDGFRα-deleted KO mice (d) Western blotting analyses; densitometry values normalized to that of β-actin are shown. *P？<？0.05, compared to that of TAA-untreated WT mice. **P？<？0.05, compared to WT mice under identical condition