Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma

a Reverse transcription-PCR (RT-PCR) assay revealed that miR-708 expression was down-regulated in high-grade glioma cell lines compared to that in low-grade glioma cell line (H4). b miR-708 was significantly decreased in glioma samples, as compared to normal brain tissue