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-  2018 

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

DOI: 10.1186/s12933-018-0803-z

Keywords: Dipeptidyl peptidase-4 inhibitors, Diabetic cardiomyopathy, Diabetes mellitus, Mitochondrial function, Mitochondrial biogenesis

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Abstract:

Representative echocardiographic images of the left ventricle for the three different groups. Two-dimensional echocardiographic image of the control group, diabetic group and alogliptin-treated diabetic group (A–C, top) and Doppler tissue imaging (bottom). LV left ventricle, RV right ventricle; AO aorta, e′ early diastolic mitral annular velocity, a′ late diastolic mitral annular velocity, n?=?10 per grou

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