Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis

a, b Circulating ALT level; c, d circulating IL-6 level; and e, f circulating HMGB1 level in WT and GsdmD？/？ mice at 6？h after HS/R or APAP. g, h Circulating ALT level in WT and GsdmD？/？ mice at 24？h after HS/R or 12？h after APAP. Each symbol in the graphs represents an individual mouse. N？=？3–10 per experimental group. Horizontal bar shows mean. *p？<？0.05 between indicated groups; **p？<？0.001 between the indicated group