Cancer cell-derived immunoglobulin G activates platelets by binding to platelet FcγRIIa

Washed platelets from healthy volunteers (n？=？20) and patients with hepatocellular carcinoma (HCC) (n？=？30), bladder cancer (n？=？22) or cervical cancer (n？=？30) were prepared, and the expression of CD62P was detected by flow cytometry. Representative curves are shown in a. The corresponding scatter diagram is shown in b and the data are represented as the mean？±？SEM. ***P？<？0.001 compared with normal platelet. PLT platele