NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression

a Representative images of immunofluorescence detection of NAA40 (green) on tissue microarrays containing a total of 318 normal and cancer colon tissues. Cell nuclei were visualized using DAPI staining (blue). Scale bar, 50？μm. b Graph showing the percentage of NAA40 positive and negative staining in normal adjacent tissues (n？=？56), benign lesions (n？=？30), and adenocarcinomas (n？=？232). c Meta-analysis of NAA40 mRNA expression levels extracted from the TCGA data portal in 647 colorectal cancer (CRC; COAD, n？=？480 and READ, n？=？167) and 51 normal patient samples (colon normal, n？=？41 and rectum normal, n？=？10). The Mann–Whitney test was used for the statistical analysis (***p？<？0.001