Effects of hypoglycemia on myocardial susceptibility to ischemia–reperfusion injury and preconditioning in hearts from rats with and without type 2 diabetes

Experimental protocols. After stabilization (Stabil) ischemic preconditioning (IPC) was induced by two periods of 5 min of global ischemia followed by 5 min of reperfusion prior to ischemia in diabetic (DM) control, Non-DM control, DM IPC and Non-DM IPC heart